CT Scans Can Help Predict CRS Recurrence with Nasal Polyps


A ratio of the sinus scores can be calculated based on CT imaging to help predict the recurrence of chronic rhinosinusitis (CRS) with nasal polyps accurately. 

According to new findings;

·         CRS with nasal polyps will always recur even after sinus surgery. The recurrence rate is at 21% within 8 years. The tissue eosinophil counts and proportions, and the presence of eosinophilicmucin have already been used as recurrence markers but the tests are often invasive or require surgery. Investigators suggest that CT scans have the potential to predict the CRS recurrence with nasal polyps.

·         The current study is investigating the importance of CT scans in predicting recurrence in CRS with nasal polyps patients who are to undergo the endoscopic functional sinus surgery. The patients already took a CT scan before surgery.

·         Two radiologists scored the scans and also assessed the maxillary sinus score (M score) as well as the total ethmoid sinus score (E score) of both sides of sinuses. The scores were used to calculate the ratio of the E score to the M score.

·         The rest of the patients in the study went through a follow up after 24 months from surgery. They were found to have a CRS with nasal polyps recurrence. The characteristics identified by the investigators include tissue eosinophil percentage, E/M ratio, and tissue eosinophil absolute count with good specificity and sensitivity. These were specifically high in the recurrence group.

The study concluded that a CT scan could help many patients to understand their recurrence risk and decide whether they can have a pharmaceutical symptom control or sinus surgery.  CT scans are non-invasive ways of predicting recurrence. Adult patients with CRS with nasal polyps should have the scan before surgery in order to determine the E/M ratio.
Location: Irving, TX, USA

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